Irell & Manella Graduate School of Biological Sciences Faculty
AR-DMRI/Diabetes & Cancer Discovery Science
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John S. Kaddis, Ph.D.
City of Hope's John Kaddis, Ph.D., is an associate professor in the Department of Diabetes & Cancer Discovery Science focusing on type 1 diabetes.
AR-DMRI/Diabetes & Cancer Metabolism
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Charles Brenner, Ph.D.
The Brennar Lab dissects the disturbances of the four nicotinamide adenine dinucleotide (NAD) coenzymes — the central catalysts of metabolism — to develop tools that improve health.
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The Deng laboratory studies the homeostasis of uridine and its role in metabolism, which provides a new angle for understanding the pathophysiology of obesity, diabetes and cancer.
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Enrique Montero, M.D., Ph.D., is a research professor within the Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope.
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Sarah Shuck, Ph.D.
The Sarah Shuck lab is investigating the biochemistry involved when excess sugar damages important molecules such as proteins and DNA.
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The Zhao Wang lab focuses on pathological cardiac remodeling due to cardiac hypertrophy, heart failure, cancer treatment, myocardial infarction, senescence and diabetes.
Diabetes, Endocrinology & Metabolism
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Ping H. Wang, M.D., is chair of the Department of Diabetes, Endocrinology & Metabolism at City of Hope.
Diabetes Complications & Metabolism
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David K. Ann, Ph.D.
David K. Ann, Ph.D., is the Morgan & Helen Chu Dean’s Chair of the Graduate School of Biological Sciences.
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Dustin E. Schones, Ph.D., is a researcher with a focus in cancer, obesity and diabetes complications as well as a professor in the Department of Diabetes Complications & Metabolism at the Diabetes & Metabolism Research Institute.
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Ke Ma, M.D., Ph.D.
Ke Ma, M.D., Ph.D., is an associate professor in the Department of Diabetes Complications & Metabolism.
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Rama Natarajan, Ph.D.
Rama Natarajan is the National Business Products Industry Endowed Chair in Diabetes Research, professor and chair in the Department of Diabetes Complications & Metabolism at City of Hope.
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Zhen Bouman Chen, Ph.D.
Zhen Bouman Chen, Ph.D., is an associate professor in the Department of Diabetes Complications & Metabolism at Beckman Research Institute of City of Hope in Duarte, California.
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Wendong Huang
Diabetes Immunology
Cancer Biology and Molecular Medicine
Shiuan Chen, Ph.D.
Shiuan Chen, Ph.D., chairs the Department of Cancer Biology and Molecular Medicine at the Beckman Research Institute of City of Hope.
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WenYong Chen, Ph.D.
WenYong Chen, Ph.D. is an Associate Professor in the Department of Cancer Biology and Molecular Medicine at the Beckman Research Institute of City of Hope.
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Robert Hickey, Ph.D.
Robert Hickey, Ph.D., is an Associate Professor in the Department of Cancer Biology and Molecular Medicine at the Beckman Research Institute of City of Hope.
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David Horne, Ph.D.
David Horne, Ph.D., vice provost and deputy director of Beckman Institute of the City of Hope and dean of Faculty Affairs, helps shape the scientific and educational vision of City of Hope with his research expertise in Medicinal Chemistry, Drug Development, and Molecular Medicine.
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Tijana Jovanovic-Talisman, Ph.D.
Tijana Jovanovic-Talisman, Ph.D., is an Associate Professor in the Department of Cancer Biology and Molecular Medicine at Beckman Research Institute of City of Hope
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John Termini, Ph.D., is Associate Director of Shared Resources at City of Hope's comprehensive cancer center. He is also a professor of molecular medicine.
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City of Hope's John Williams, Ph.D., is a professor in the Department of Cancer Biology and Molecular Medicine and Director of the X-ray Crystallography Core.
Cancer Genetics & Epigenetics
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Chun-Wei (David) Chen, Ph.D.
David Chen, Ph.D., is an associate professor and director of the Division of Epigenetic and Transcriptional Engineering in the Department of Systems Biology
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Binghui Shen, Ph.D.
Enzymology of DNA Replication and Repair; Etiological Mouse Models of Cancer
Using genetic mouse models of cancer, Dr. Shen studies enzymes and mechanisms involved in the DNA replication-coupled repair, such as Okazaki fragment maturation and repair of DNA damage that is caused by radiation and by
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Jeremy Stark, Ph.D. is a Professor of Cancer Genetics and Epigenetics
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Yilun Liu, Ph.D.
Yilun Liu, Ph.D., is a professor and associate chair of the Department of Cancer Genetics and Epigenetics.
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Yanzhong (Frankie) Yang, M.D., Ph.D.
Yanzhong (Frankie) Yang, M.D., Ph.D., is an associate professor in the Department of Cancer Genetics and Epigenetics at Beckman Research Institute of City of Hope.
Center for Comparative Medicine
City of Hope's Richard Ermel Directs and oversees the DCM biomedical and translational research programs.
Center for Gene Therapy
Center for RNA Biology & Therapeutics
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City of Hope's Keiichi Itakura, Ph.D., is a professor emeritus, Center for RNA Biology and Therapeutics, and his research focus in on recombinant DNA technology.
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Ren-Jang Lin, Ph.D., is a professor in the Center fo RNA Biology and Therapeutics, conducting research focusing on the role of RNA splicing and microRNAs in cancer.
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Marcia Miller, Ph.D.
Marcia Miller, Ph.D., Professor Emeritus, Center for RNA Biology and Therapeutics, and the Director Emeritus of the Electron Microscopy Core Facility at City of Hope in Los Angeles, CA.
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John Rossi, Ph.D., is dean emeritus of the Irell & Manella Graduate School of Biological Sciences, professor and chair in the Department of Mollecular and Cellular Biology, and founding director of the Center for RNA Biology and Thererapeutics at Beckman Research Institute of City of Hope
Computational & Quantitative Medicine
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Sergio Branciamore, Ph.D.
Dr. Branciamore's research interests include (i) investigating the impact of epigenetics on development, disease and evolution, (ii) the application of methods from statistical mechanics and dynamical systems to personalized medicine for the treatment of complex diseases and cancer, and (iii) the
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Zhaohui Gu, Ph.D.
Dr. Gu’s research focus is to integrate multi-omics platforms, advanced analytical approaches, and multiple experimental models to study the heterogeneity of acute leukemias and facilitate the development of more efficacious targeted therapies.
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Joycelynne Palmer, Ph.D.
Dr. Palmer’s research interests and effort support preclinical and clinical studies concerning the major obstacles to disease control/cure of hematologic malignancies and successful hematopoietic stem cell transplantation.
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Andrei S. Rodin, Ph.D.
Andrei S. Rodin, Ph.D., research interests are (i) computational systems biology — both methodology development and application to diverse high-dimensional multiscale biomedical data, and (ii) molecular evolution.
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Russell Rockne, Ph.D.
Dr. Rockne serves as director of the Division of Mathematical Oncology and Computational Systems Biology, with the goal of translating mathematics, physics and evolution-based research to clinical care.
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Nagarajan Vaidehi, Ph.D.
Nagarajan Vaidehi, Ph.D., is a scientist, educator and leader with a career-long commitment to developing computational methods to simulate dynamics of proteins involved in signal transduction pathways and using them for the discovery of next generation drugs with lower side effects. Dr. Vaidehi is
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Xiwei Wu, Ph.D.
Dr. Wu’s research interests are in development and application of innovative state-of-the-art bioinformatics techniques and tools that span basic and translational research areas pertaining to genome technologies.
Hematologic Malignancies Translational Science
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Ya-Huei Kuo, Ph.D.
Ya-Huei Kuo, Ph.D., is a professor in the Department of Hematologic Malignancies Translational Science with a research focus in leukemia biology.
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Guido Marcucci, M.D.
Guido Marcucci, M.D., is professor and chair of the Department of Hematological Malignancies Translational Science and chief of the Division of Leukemia.
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Ling Li, Ph.D.
Ling Li, Ph.D., is an associate professor in Beckman Research Institute's Department of Hematologic Malignancies Translational Science.
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Flavia Pichiorri, Ph.D., M.S.
Flavia Pichiorri, Ph.D., M.S., is a professor in the Department of Hematologic Malignancies Translational Science.
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Bin Zhang, Ph.D.
Bin Zhang, Ph.D., is an associate professor in the Department of Hematologic Malignancies Translational Science.
Hematology & Hematopoietic Cell Transplantation
Christine Brown, Ph.D., is deputy director of the T Cell Therapeutics Research Laboratory at Beckman Research Institute of City of Hope.
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Elizabeth Budde, M.D., Ph.D., is an oncologist and associate professor at City of Hope.
Michael Caligiuri, M.D.
Michael A. Caligiuri, M.D., is a world-renowned physician, scientist, builder, innovator, leader and visionary. He is dedicated to developing the next generation of leading-edge cancer therapies.
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Dr. Danilov is the associate director of the Toni Stephenson Lymphoma Center and professor in the Department of Hematology & Hematopoietic Cell Transplantation.
Don J. Diamond, Ph.D.
Don J. Diamond, Ph.D., is Professor in the Department of Hematology & Hematopoietic Cell Transplantation.
Stephen J. Forman, M.D., hematologist-oncologist, is a top cancer doctor for leukemia, lymphoma and bone marrow transplantation. He is also the director of the Hematologic Malignancies Research Institute & director of the T Cell Therapeutics Research Laboratory at City of Hope, Duarte, California.
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Larry W. Kwak, M.D., Ph.D.
Larry Kwak, M.D., Ph.D., is the director of the Toni Stephenson Lymphoma Center at City of Hope.
Steven T. Rosen, M.D.
Steven T. Rosen, M.D., is a professor, Division of Lymphoma, Department of Hematology & Hematopoietic Cell Transplantation, and executive vice president and director emeritus, Comprehensive Cancer Center and Beckman Research Institute of City of Hope.
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Marcel van den Brink, M.D., Ph.D.
Marcel van den Brink, M.D., Ph.D., is the president of City of Hope Cancer Center, main campus in Los Angeles, National Medical Center, chief physician executive and the Deana and Steve Campbell Chief Physician Executive Distinguished Chair.
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Xiuli Wang, Ph.D.
Xiuli Wang, Ph.D., is a professor in City of Hope's Department of Hematology & Hematopoietic Cell Transplantation.
Immunology & Theranostics
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Markus Kalkum, Ph.D., is a professor in the Department of Immunology & Theranostics and co-director of the Mass Spectrometry and Proteomics Core.
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Helena Reijonen, Ph.D., is an associate professor in the Department of Immunology & Theranostics, City of Hope, California.
John Shively, Ph.D., is a professor in the Department of Immunology & Theranostics within the Diabetes & Metabolism Research Institute at City of Hope.
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Anna Wu, Ph.D., is chair of the Department of Immunology & Theranostics and co-director of the Center for Theranostic Studies.
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Kirstin A. Zettlitz, Ph.D.
Kirstin Anja Zettlitz, Ph.D., is an assistant professor in the Department of Immunology & Theranostics within the Diabetes & Metabolism Research Institute at City of Hope.
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Defu Zeng, Ph.D.
Defu Zeng, is a professor of immunology & theranostics and hematologist. His focus is on transplantation immune tolerance.
Immuno-Oncology
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Javier Gordon Ogembo, Ph.D., is associate professor in the Department of Immuno-Oncology at Beckman Research Institute of City of Hope.
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Marcin Kortylewski, Ph.D.
Marcin Kortylewski, Ph.D., is a professor in the Department of Immuno-Oncology, focuses on cancer immunotherapy.
Peter P. Lee, M.D., is professor and chair in the department of Immuno-Oncology, Beckman Research Institute of City of Hope in Southern California and beneficiary of The Christopher Family Endowed Innovation Fund for Alzheimer’s Disease and Breast Cancer Research in Honor of Vineta Christopher.
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Leo David Wang, M.D., Ph.D., is a pediatric hematologist-oncologist and associate professor in the departments of Immuno-Oncology and Pediatrics.
Hua Yu, Ph.D.
Hua Yu, Ph.D., associate chair of the Department of Immuno-Oncology, has made STAT3 the focus of much of her research.
Integrative Translational Sciences
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Enrique Velazquez Villarreal, M.D., Ph.D., M.P.H., M.S.
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Crystal Marconett, Ph.D.
Crystal Marconett, Ph.D., brings her combined expertise in bioinformatics and molecular biology to City of Hope’s lung cancer research program, in the role of associate professor in the Department of Integrative Translational Sciences
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David W. Craig, Ph.D.
David W. Craig, Ph.D., is the founding chair of the Department of Integrative Translational Sciences at City of Hope and incoming deputy director of Translational Sciences at the Beckman Research Institute of City of Hope.
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John D. Carpten, Ph.D.
John D. Carpten, Ph.D., City of Hope’s chief scientific officer, was named a top diversity leader in U.S. health care by Modern Healthcare magazine, which honors influential U.S. health care executives for their commitment to improving equity and inclusion at their organization and in the industry.
Medical Oncology & Therapeutics Research, Clinical Cancer Genomics
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Sumanta Kumar Pal, M.D., FASCO, is an internationally recognized leader in the area of genitourinary cancers. He is the co-director of City of Hope's Kidney Cancer Program and is the head of the kidney and bladder cancer disease team at the institution.
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Aritro Nath, Ph.D., is an Assistant Professor in the Department of Medical Oncology & Therapeutics Research
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Edward Newman, Ph.D.
Edward Newman, Ph.D. is an Associate Professor Emeritus in the Department of Medical Oncology & Therapeutics Research & co-director of the Analytical Pharmacology Core.
Marwan G. Fakih, M.D., is a medical oncologist specializing in gastrointestinal cancers.
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Ravi Salgia, M.D., Ph.D.
Ravi Salgia M.D., Ph.D., is the Arthur & Rosalie Kaplan Chair in Medical Oncology at City of Hope and an expert in the study and treatment of lung cancer, mesothelioma, thoracic and thymic malignancies and bronchial carcinoids.
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Stephen Gruber, M.D., Ph.D., M.P.H.
A world-renowned cancer geneticist, Stephen Gruber, M.D., Ph.D., M.P.H., focuses his research on precision medicine and the genomics of cancer in order to improve treatment and care for cancer patients and their families.
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Timothy Synold, Pharm.D.
Timothy Synold, Pharm,D., is director of the Analytical Pharmacology Core, and a professor in the Department of Medical Oncology & Therapeutics Research at City of Hope.
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Stacy W. Gray, M.D., is deputy director of the Center for Precision Medicine and professor and chief of the Division of Clinical Cancer Genomics within the Department of Medical Oncology & Therapeutics Research, and a secondary appointment in the Department of Population Sciences.
Medicine
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June-Wha Rhee, M.D.
June-Wha Rhee, M.D.,is a cardio-oncology assistant professor in the Division of Cardiology in the Department of Medicine, assistant professor in the Department of Stem Cell Biology and Regenerative Medicine at Beckman Research Institute of City of Hope.
Molecular & Cellular Endocrinology
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Adolfo Garcia-Ocaña, Ph.D.
Chair, Department of Molecular & Cellular Endocrinology; Ruth B. and Robert K. Lanman Endowed Chair in Gene Regulation and Drug Discovery Research
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Debbie C. Thurmond, Ph.D.
Debbie C. Thurmond, Ph.D., is director of the Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope and chair and professor in the Department of Molecular & Cellular Endocrinology.
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Patrick Fueger, Ph.D.
Patrick Fueger is an Associate Professor, Department of Molecular & Cellular Endocrinology.
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Qiong (Annabel) Wang, Ph.D.
Qiong (Annabel) Wang, Ph.D. is an assistant professor in the Department of Molecular & Cellular Endocrinology.
Molecular Diagnostics & Experimental Therapeutics
Linda Malkas, Ph.D.
Linda Malkas, Ph.D., is a professor in the Department of Molecular Diagnostics & Experimental Therapeutics at Beckman Research Institute of City of Hope.
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Ajay Goel, Ph.D., AGAF
Ajay Goel, Ph.D., AGAF, associate director of basic science, comprehensive cancer center; professor and chair, Department of Molecular Diagnostics and Experimental Therapeutics, researches molecular pathogenesis of human gastrointestinal cancers and its relationship to early detection of cancer
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Jeff Perry, Ph.D., is an assistant professor in the Ajay Goel lab in the Department of Molecular Diagnostics and Experimental Therapeutics at City of Hope in Duarte, California.
Neurodegenerative Diseases
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Yanhong Shi, Ph.D.
Disease modeling and therapeutic development for neurological diseases and cancer.
Pathology
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Christiane Querfeld, M.D., Ph.D., is a dermatologist and dermatopathologist who specializes in the diagnosis and treatment of cutaneous lymphoma.
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John Chan, M.D., is a hematopathologist and co-leader of the hematology malignancies program at City of Hope Cancer Center.
Pediatrics
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For Lior Goldberg, M.D., his work as pediatric oncologist centers around curiosity, compassion and courage. He makes sure to genuinely get to know the patients and families he serves, sharing in the difficult aspects of cancer and its treatment while helping ease distress.
Population Sciences
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Pediatric hematologist-oncologist Saro Armenian, D.O., M.P.H., is the Barron Hilton Chair in Pediatrics, with expertise in pediatric cancer, epidemiology and cancer survivorship.
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Marta Jankowska received her Ph.D. at San Diego State University and University of California, Santa Barbara, where she also did postdoctoral work in family medicine and public health.
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Mark LaBarge is a Professor in the Department of Population Sciences with a focus on breast cancer research.
Susan L. Neuhausen, Ph.D.
Susan L. Neuhausen, Ph.D., is The Morris & Horowitz Families Professor in Cancer Etiology & Outcomes Research at Beckman Research Institute of City of Hope. She conducts research focused on identifying genes that predispose to disease.
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Narissa Nonzee, Ph.D.
Narissa Nonzee, Ph.D., is a health services researcher and Assistant Professor in the Division of Health Equities within the Department of Population Sciences at City of Hope.
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Victoria Seewaldt, M.D., is the Ruth Ziegler Chair in Population Sciences and chair and professor of the Department of Population Sciences, with a clinical specialty in breast cancer.
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Christopher Sistrunk, Ph.D., is an associate professor in the Department of Population Sciences at City of Hope
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Lindsey S. Treviño, Ph.D.
Lindsey S. Treviño, Ph.D. is an assistant professor in the Division of Health Equities and Department of Population Sciences.
Radiation Oncology
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Susanta Hui, Ph.D., is a Professor, Department of Radiation Oncology at City of Hope in Duarte, CA.
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Terence M. Williams, M.D., Ph.D., is professor and chair of the Department of Radiation Oncology, City of Hope in Duarte, Southern California.
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Yun Rose Li, M.D., Ph.D.
Yun Rose Li, M.D., Ph.D., is an assistant professor in the Department of Radiation Oncology at City of Hope.
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Heather McGee, M.D., Ph.D.
Heather McGee, M.D., Ph.D., is an assistant professor in the Department of Radiation Oncology and Department of Immuno-Oncology at City of Hope.
Stem Cell Biology & Regenerative Medicine
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Carlotta Glackin, Ph.D.
Transcriptional Control of Tumor Cell Dissemination and Metastasis.
Karen Aboody, M.D.
Translational Research - Neural Stem Cell as Delivery tool for Cancer Treatment.
Michael Barish, Ph.D.
At the Intersection of neurobiology and immuno-oncology.
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Nadia Carlesso, Ph.D.
Modulation of the bone marrow niche to redirect cellular networks in stress and malignant hematopoiesis
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Regenerative medicine for Traumatic Brain Injury.
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Qiang Lu, Ph.D.
Regulation of Neural Progenitor Cell Proliferation and Differentiation in Brain Development and Tumor Formation.
Surgery
Behnam Badie, M.D., is a renowned neurosurgeon and expert in the field of surgical neuro-oncology, nanotechnology and T cell research.
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Ellie Maghami, M.D.
Ellie Maghami, M.D., is a head, neck and thyroid cancer surgeon and The Norman and Sadie Lee Foundation Endowed Professor in Head and Neck Cancer.
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A prolific researcher and talented surgeon, Mike Y. Chen, M.D., Ph.D., has been on City of Hope's neurosurgery team since 2007. He specializes in complex operations for the removal of brain and spine tumors.
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Mustafa Raoof, M.D., M.S., is a surgical oncologist and an assistant professor in the Department of Surgery and in the Department of Cancer Genetics and Epigenetics.
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City of Hope's neurosurgeon and scientist, Rahul Jandial, M.D., Ph.D., specializes in brain, spine and spinal cord cancers.
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Saswati Chatterjee, Ph.D., is a professor in the Department of Surgery conducting research focusing on evaluating genetic modification of hematopoietic stem cells.
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Thanh H. Dellinger, M.D., is a gynecologic oncologist focusing on ovarian cancer, cervical cancer, uterine cancer, robotic surgery and fertility sparing cancer treatments.
Yuman Fong, M.D., is an internationally recognized expert in cancer of the liver, pancreas, gallbladder and bile ducts. He has led the research effort to employ genetically modified viruses to destroy cancer cells.
Systems Biology
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Nora Heisterkamp, Ph.D. is a researcher in the Department of Systems Biology in Beckman Research Institute of City of Hope.
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Jianjun Chen, Ph.D.
Jianjun Chen, Ph.D., is the Simms/Mann Family Foundation Chair in Systems Biology, professor and chair in the Department of Systems Biology, and director for the Center for RNA Biology and Therapeutics at City of Hope.
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Lili Wang, M.D., Ph.D., is a professor in the Department of Systems Biology.
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Mark Boldin, Ph.D., is an associate professor, in the Department of Systems Biology, at Beckman Research Institute of City of Hope. His focus is on leukemia and stem cell biology research.
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Rui Su, Ph.D., is an assistant professor in the Department of Systems Biology.
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Vu Nguyen Ngo, Ph.D., is an associate professor in the Department of Systems Biology at Beckman Research Institute of City of Hope.
Translational Genomics Research Institute (TGen)
Translational Research & Cellular Therapeutics
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Ben Shih, Ph.D.
Ben Hung Ping Shih, Ph.D., is an associate professor at City of Hope's Arthur Riggs Diabetes & Metabolism Research Institute.
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Jiing Kuan Yee, Ph.D.
Jiing Kuan Yee, Ph.D., is a professor, researcher and is expert in the development of genome editing for disease modeling and cell-based therapy at Beckman Research Institute of City of Hope.
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Rupangi Vasavada, Ph.D.
Rupangi Vasavada, Ph.D., is an associate professor in the Department of Translational Research & Cellular Therapeutics
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Sangeeta Dhawan, Ph.D.
Sangeeta Dhawan, Ph.D., is an associate professor in the Department of Translational Research & Cellular Therapeutics within the Arthur Riggs Diabetes & Metabolism Research Institute.
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Teresa Ku, Ph.D.
Teresa Ku, Ph.D., | Associate Professor, Translational Research & Cellular Therapeutics | City of Hope